Kobe International Cell Therapy Center

Japan’s Longest-Established Regenerative Medicine Institute with In-House Cell Cultivation Lab.

13 Years of Excellence — From Kobe to the World, Leading Global Advanced Medicine.

Japan’s Leading Regenerative Medicine – Empowering Global Patients with New Hope for Health.

The Longest-Established Regenerative Medicine Institution

We are Japan’s longest-established regenerative medicine institution, with over 13 years of dedicated experience in stem cell and immune cell therapies. Founded in 2012, we remain at the forefront of the field through consistent clinical innovation and excellence.

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Strict Standards & Equipped with CPC

Our CPC (Cell Processing Center) operates under strict regulatory standards. Our specified cell-processed products have passed rigorous reviews and are approved by Japan’s Minister of Health, Labour and Welfare. All cells are cultured, managed, and preserved by certified technicians in a sterile cleanroom environment.

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Extensive Treatment Experience

Regenerative medicine uses the patient’s own cultured stem cells, offering a low risk of side effects and a wide range of clinical applications. Mesenchymal stem cells (MSCs), which can differentiate into various cell types, were originally derived from bone marrow and are now commonly extracted from adipose tissue. We have accumulated thousands of clinical cases and earned the trust of our patients. With thousands of clinical treatment cases, we have earned the trust of many patients.

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3 Major Characteristics of Mesenchymal Stem Cells

Multipotent Differentiation

Mesenchymal stem cells (MSCs) can divide and differentiate into various tissue cell types, including bone, cartilage, fat, muscle, blood vessels, and nerves.

Immunosuppressive Function

MSCs help regulate inflammation and immune activity, contributing to immune system balance. They have also been studied for use alongside immunosuppressants in transplantation.

Homing Ability

MSCs have the unique ability to migrate toward and accumulate at sites of tissue injury—known as “homing”—where they contribute to tissue repair and regeneration.

What is MSC Therapy?

OUR TREATMENT

By utilizing the regenerative and reparative functions of stem cells, MSC therapy treats conditions such as liver dysfunction, chronic pain, neurological and immune system disorders, helping patients improve their health and restore bodily functions.

Liver Dysfunction

Liver dysfunction has various types and causes, with the most common being fatty liver and viral hepatitis. Fatty liver occurs when excess fat accumulates in the liver due to overeating or obesity, triggering the disease. This accumulation can impair normal liver function and may lead to inflammation or the progression of fibrosis.

Facial Conditions & Skin Regeneration

Atrophy of the facial dermis and subcutaneous fat causes localized facial depressions and deformities, commonly seen in Parry-Romberg syndrome and collagen diseases. Fat injections combined with stem cells are expected to restore a naturally full facial appearance.

Chronic Pain

For chronic pain lasting more than three months and unresponsive to conventional treatments, stem cells can help relieve pain by inhibiting inflammation that causes pain and repairing damaged nerve cells and tissues.

Degenerative Knee Joint Disease

Knee joint degeneration, characterized by cartilage wear and joint deformity, can be improved by injecting stem cells into the knee joint. This treatment alleviates knee pain and protects cartilage, making it especially suitable for elderly patients.

Cerebrovascular Disorders (Stroke)

Stem cell therapy promotes repair of damaged cerebral blood vessels and angiogenesis, thereby improving central nervous system disorders and functional impairments. It is suitable for patients with sequelae of cerebral infarction.

Neurodegenerative Diseases

For diseases such as Parkinson’s disease, spinocerebellar degeneration, and Alzheimer’s disease, stem cells are expected to slow disease progression and improve symptoms through their anti-inflammatory and neuroprotective effects.

Spinal Cord Injury

Stem cells aim to alleviate sequelae such as limb paralysis, sensory disorders, and excretory dysfunction caused by spinal cord injury by repairing damaged spinal nerve tissue.

Alzheimer’s Disease

By regenerating nerve cells and promoting angiogenesis through stem cells, blood flow is improved, aiming to enhance cognitive function, maintain daily living abilities, and inhibit the progression of brain atrophy.

Atopic dermatitis

Stem cells can improve immune abnormalities, repair skin inflammation and barrier function, and significantly alleviate itching symptoms.

Rheumatoid arthritis

For autoimmune diseases such as rheumatoid arthritis, stem cell therapy not only helps regulate the immune system and reduce inflammation but also promotes the regeneration of damaged joint cartilage.

Post-COVID-19 Syndrome

Stem cell therapy can improve post-COVID symptoms such as persistent fatigue, low-grade fever, difficulty breathing, cough, loss of smell and taste, hair loss, and decreased concentration.

Crohn’s Disease

Crohn’s disease is an inflammatory condition of the digestive system. Stem cell therapy helps suppress inflammation, improve intestinal barrier and immune function, and alleviate symptoms such as bloody stools and diarrhea.

Type 2 Diabetes & Borderline Diabetes

The cells collected during this procedure will be used for “autologous adipose-derived stem cell therapy for type 2 diabetes and borderline diabetes.”

All Conditions Treated

Regenerative Medicine Plan License

Stem Cell Certificates

Cell Culture Processing Facility (CPC) Licensed by Japan Ministry of Health, Labour and Welfare

NB5150011

Submitted Regenerative Medicine Provision Plans

Kobe Harborland immunotherapy clinic is a medical institution that has submitted second- and third-class regenerative medicine provision plans to the Japan Ministry of Health, Labour and Welfare and obtained plan numbers.

Name of Regenerative Medicine	License Number
Treatment of diabetes and pre-diabetes using autologous adipose-derived stem cells	PB5240108
Treatment of liver dysfunction using autologous adipose-derived stem cells	PB5210015
Treatment of facial atrophy and skin regeneration with autologous adipose-derived stem cells	PB5210014
Treatment of central nervous system dysfunction using autologous adipose-derived stem cells	PB5220010
Treatment of chronic pain using autologous adipose-derived stem cells	PB5220011
Treatment of autoimmune diseases using autologous adipose-derived stem cells	PB5220012
Treatment of osteoarthritis using autologous adipose-derived stem cells	PB5240016
Dendritic cell vaccine therapy for the treatment and prevention of recurrence of malignant neoplasms	PC5150140
Activated T lymphocyte therapy for the treatment and prevention of recurrence of malignant neoplasms	PC5150138
Natural killer (NK) cell therapy for the treatment and prevention of recurrence of malignant neoplasms	PC5150139
NKT cell therapy using dendritic cells for the treatment and prevention of recurrence of malignant tumors	PC5190043

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